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Short-term memory advantage for brief durations in human APOE ε4 carriers

The Apolipoprotein-E (APOE) ε4 gene allele, the highest known genetic risk factor for Alzheimer’s disease, has paradoxically been well preserved in the human population. One possible explanation offered by evolutionary biology for survival of deleterious genes is antagonistic pleiotropy. This theory...

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Detalles Bibliográficos
Autores principales: Zokaei, Nahid, Grogan, John, Fallon, Sean James, Slavkova, Ellie, Hadida, Jonathan, Manohar, Sanjay, Nobre, Anna Christina, Husain, Masud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289888/
https://www.ncbi.nlm.nih.gov/pubmed/32528115
http://dx.doi.org/10.1038/s41598-020-66114-6