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KDM3A/Ets1/MCAM axis promotes growth and metastatic properties in Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy of childhood. RMS exists as two major disease subtypes, with oncofusion-positive RMS (FP-RMS) typically carrying a worse prognosis than oncofusion-negative RMS (FN-RMS), in part due to higher propensity for metastasis. Epigenetic mecha...

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Detalles Bibliográficos
Autores principales: Sobral, Lays Martin, Sechler, Marybeth, Parrish, Janet K., McCann, Tyler S., Jones, Kenneth L., Black, Joshua C., Jedlicka, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289905/
https://www.ncbi.nlm.nih.gov/pubmed/32577157
http://dx.doi.org/10.18632/genesandcancer.200