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Challenges and Pitfalls in the Engineering of Human Interleukin 22 (hIL-22) Secreting Lactobacillus reuteri

Engineered microbes for the delivery of intestinally directed therapeutics is a promising avenue for the treatment of various intestinal diseases including inflammatory bowel disease (IBD) and intestinal graft vs. host disease (GVHD). This modality of treatment would allow for the targeted delivery...

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Detalles Bibliográficos
Autores principales: Ortiz-Velez, Laura, Goodwin, Annie, Schaefer, Laura, Britton, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289926/
https://www.ncbi.nlm.nih.gov/pubmed/32582668
http://dx.doi.org/10.3389/fbioe.2020.00543