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Challenges and Pitfalls in the Engineering of Human Interleukin 22 (hIL-22) Secreting Lactobacillus reuteri
Engineered microbes for the delivery of intestinally directed therapeutics is a promising avenue for the treatment of various intestinal diseases including inflammatory bowel disease (IBD) and intestinal graft vs. host disease (GVHD). This modality of treatment would allow for the targeted delivery...
Autores principales: | Ortiz-Velez, Laura, Goodwin, Annie, Schaefer, Laura, Britton, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289926/ https://www.ncbi.nlm.nih.gov/pubmed/32582668 http://dx.doi.org/10.3389/fbioe.2020.00543 |
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