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Berberine Mediated Positive Inotropic Effects on Rat Hearts via a Ca(2+)-Dependent Mechanism
Previous studies showed that berberine, an alkaloid from Coptis Chinensis Franch, might exert a positive inotropic effect on the heart. However, the underlying mechanisms were unclear. Here, we reported that berberine at 10–20 µM increased the left ventricular (LV) developed pressure and the maximal...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289965/ https://www.ncbi.nlm.nih.gov/pubmed/32581792 http://dx.doi.org/10.3389/fphar.2020.00821 |