Evaluation of T-Cell Responses Against Shared Melanoma Associated Antigens and Predicted Neoantigens in Cutaneous Melanoma Patients Treated With the CSF-470 Allogeneic Cell Vaccine Plus BCG and GM-CSF

The CSF-470 vaccine consists of lethally-irradiated allogeneic cells derived from four cutaneous melanoma cell lines administered plus BCG and GM-CSF as adjuvants. In an adjuvant phase II study vs. IFN-α2b, the vaccine significantly prolonged the distant metastasis-free survival (DMFS) of stages IIB...

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Detalles Bibliográficos
Autores principales: Podaza, Enrique, Carri, Ibel, Aris, Mariana, von Euw, Erika, Bravo, Alicia Inés, Blanco, Paula, Ortiz Wilczyñski, Juan Manuel, Koile, Daniel, Yankilevich, Patricio, Nielsen, Morten, Mordoh, José, Barrio, María Marcela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290006/
https://www.ncbi.nlm.nih.gov/pubmed/32582212
http://dx.doi.org/10.3389/fimmu.2020.01147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290006/
https://www.ncbi.nlm.nih.gov/pubmed/32582212
http://dx.doi.org/10.3389/fimmu.2020.01147

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