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Poincaré maps for analyzing complex hierarchies in single-cell data

The need to understand cell developmental processes spawned a plethora of computational methods for discovering hierarchies from scRNAseq data. However, existing techniques are based on Euclidean geometry, a suboptimal choice for modeling complex cell trajectories with multiple branches. To overcome...

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Detalles Bibliográficos
Autores principales: Klimovskaia, Anna, Lopez-Paz, David, Bottou, Léon, Nickel, Maximilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290024/
https://www.ncbi.nlm.nih.gov/pubmed/32528075
http://dx.doi.org/10.1038/s41467-020-16822-4