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Poincaré maps for analyzing complex hierarchies in single-cell data
The need to understand cell developmental processes spawned a plethora of computational methods for discovering hierarchies from scRNAseq data. However, existing techniques are based on Euclidean geometry, a suboptimal choice for modeling complex cell trajectories with multiple branches. To overcome...
Autores principales: | Klimovskaia, Anna, Lopez-Paz, David, Bottou, Léon, Nickel, Maximilian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290024/ https://www.ncbi.nlm.nih.gov/pubmed/32528075 http://dx.doi.org/10.1038/s41467-020-16822-4 |
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