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Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism
The high incidence of aneuploidy in the embryo is considered the principal cause for low human fecundity. However, the prevalence of aneuploidy dramatically declines as pregnancy progresses, with the steepest drop occurring as the embryo completes implantation. Despite the fact that the plasticity o...
Autores principales: | Singla, Shruti, Iwamoto-Stohl, Lisa K., Zhu, Meng, Zernicka-Goetz, Magdalena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290028/ https://www.ncbi.nlm.nih.gov/pubmed/32528010 http://dx.doi.org/10.1038/s41467-020-16796-3 |
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