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Changes in lung immune cells related to clinical outcome during treatment with infliximab for sarcoidosis

Pulmonary sarcoidosis is characterized by an exaggerated CD4(+) T cell response and formation of non‐necrotizing granulomas. Tumour necrosis factor α (TNF‐α) is regarded as crucial for granuloma formation and TNF‐α inhibitors offer a third‐line treatment option for patients not responding to convent...

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Detalles Bibliográficos
Autores principales: Kullberg, S., Rivera, N. V., Abo Al Hayja, M., Grunewald, J., Eklund, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290087/
https://www.ncbi.nlm.nih.gov/pubmed/32275772
http://dx.doi.org/10.1111/cei.13438