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Aloin promotes cell apoptosis by targeting HMGB1-TLR4-ERK axis in human melanoma cells

Aloin (ALO) is the major anthraquinone glycoside purified from the Aloe species. It is well known for its anti-tumor effects. However, the protective effects of ALO in melanoma cancer and underlying molecular mechanism remain unclear. High-mobility group protein B1 (HMGB1) is an intracellular protei...

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Detalles Bibliográficos
Autores principales: Li, Pan, Ren, Kai, Liang, Yin yin, Liu, Ji kai, Liang, Zhuo wen, Zhang, Yong feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290104/
https://www.ncbi.nlm.nih.gov/pubmed/32536835