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A High-Throughput HIV-1 Drug Screening Platform, Based on Lentiviral Vectors and Compatible with Biosafety Level-1

HIV-1 infection is a complex, multi-step process involving not only viral, but also multiple cellular factors. To date, drug discovery methods have primarily focused on the inhibition of single viral proteins. We present an efficient and unbiased approach, compatible with biosafety level 1 (BSL-1) c...

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Detalles Bibliográficos
Autores principales: Ellinger, Bernhard, Pohlmann, Daniel, Woens, Jannis, Jäkel, Felix M., Reinshagen, Jeanette, Stocking, Carol, Prassolov, Vladimir S., Fehse, Boris, Riecken, Kristoffer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290285/
https://www.ncbi.nlm.nih.gov/pubmed/32466195
http://dx.doi.org/10.3390/v12050580