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Development, Characterization, and Application of Two Reporter-Expressing Recombinant Zika Viruses

Zika virus (ZIKV), a mosquito-borne transplacentally transmissible flavivirus, is an enveloped virus with an ~10.8 kb plus-strand RNA genome that can cause neurological disease. To facilitate the identification of potential antivirals, we developed two reporter-expressing ZIKVs, each capable of expr...

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Detalles Bibliográficos
Autores principales: Yun, Sang-Im, Song, Byung-Hak, Woolley, Michael E., Frank, Jordan C., Julander, Justin G., Lee, Young-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290298/
https://www.ncbi.nlm.nih.gov/pubmed/32456014
http://dx.doi.org/10.3390/v12050572