Targeting the Early Endosome-to-Golgi Transport of Shiga Toxins as a Therapeutic Strategy

Shiga toxin (STx) produced by Shigella and closely related Shiga toxin 1 and 2 (STx1 and STx2) synthesized by Shiga toxin-producing Escherichia coli (STEC) are bacterial AB(5) toxins. All three toxins target kidney cells and may cause life-threatening renal disease. While Shigella infections can be...

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Detalles Bibliográficos
Autores principales: Li, Danyang, Selyunin, Andrey, Mukhopadhyay, Somshuvra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290323/
https://www.ncbi.nlm.nih.gov/pubmed/32456007
http://dx.doi.org/10.3390/toxins12050342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290323/
https://www.ncbi.nlm.nih.gov/pubmed/32456007
http://dx.doi.org/10.3390/toxins12050342

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