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Targeting the Early Endosome-to-Golgi Transport of Shiga Toxins as a Therapeutic Strategy
Shiga toxin (STx) produced by Shigella and closely related Shiga toxin 1 and 2 (STx1 and STx2) synthesized by Shiga toxin-producing Escherichia coli (STEC) are bacterial AB(5) toxins. All three toxins target kidney cells and may cause life-threatening renal disease. While Shigella infections can be...
Autores principales: | Li, Danyang, Selyunin, Andrey, Mukhopadhyay, Somshuvra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290323/ https://www.ncbi.nlm.nih.gov/pubmed/32456007 http://dx.doi.org/10.3390/toxins12050342 |
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