Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Artery as Major Producer of CYP450-Derived Epoxy Fatty Acids

A number of oxylipins have been described as endogenous PPAR ligands. The very short biological half-lives of oxylipins suggest roles as autocrine or paracrine signaling molecules. While coronary arterial atherosclerosis is the root of myocardial infarction, aortic atherosclerotic plaque formation i...

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Detalles Bibliográficos
Autores principales: Edin, Matthew L., Lih, Fred B., Hammock, Bruce D., Thomson, Scott, Zeldin, Darryl C., Bishop-Bailey, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290345/
https://www.ncbi.nlm.nih.gov/pubmed/32365470
http://dx.doi.org/10.3390/cells9051096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290345/
https://www.ncbi.nlm.nih.gov/pubmed/32365470
http://dx.doi.org/10.3390/cells9051096

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