Secretome of Mesenchymal Stromal Cells Prevents Myofibroblasts Differentiation by Transferring Fibrosis-Associated microRNAs within Extracellular Vesicles

Fibroblasts differentiation into myofibroblasts is a central event of tissue fibrosis. Multipotent mesenchymal stromal cells (MSCs) secretome can interfere with fibrosis development; despite precise underlying mechanisms remain unclear. In this study, we tested the hypothesis that MSC secretome can...

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Detalles Bibliográficos
Autores principales: Basalova, Nataliya, Sagaradze, Georgy, Arbatskiy, Mikhail, Evtushenko, Evgeniy, Kulebyakin, Konstantin, Grigorieva, Olga, Akopyan, Zhanna, Kalinina, Natalia, Efimenko, Anastasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290371/
https://www.ncbi.nlm.nih.gov/pubmed/32443855
http://dx.doi.org/10.3390/cells9051272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290371/
https://www.ncbi.nlm.nih.gov/pubmed/32443855
http://dx.doi.org/10.3390/cells9051272

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