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Secretome of Mesenchymal Stromal Cells Prevents Myofibroblasts Differentiation by Transferring Fibrosis-Associated microRNAs within Extracellular Vesicles
Fibroblasts differentiation into myofibroblasts is a central event of tissue fibrosis. Multipotent mesenchymal stromal cells (MSCs) secretome can interfere with fibrosis development; despite precise underlying mechanisms remain unclear. In this study, we tested the hypothesis that MSC secretome can...
Autores principales: | Basalova, Nataliya, Sagaradze, Georgy, Arbatskiy, Mikhail, Evtushenko, Evgeniy, Kulebyakin, Konstantin, Grigorieva, Olga, Akopyan, Zhanna, Kalinina, Natalia, Efimenko, Anastasia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290371/ https://www.ncbi.nlm.nih.gov/pubmed/32443855 http://dx.doi.org/10.3390/cells9051272 |
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