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Functional Consequences of the Variable Stoichiometry of the Kv1.3-KCNE4 Complex

The voltage-gated potassium channel Kv1.3 plays a crucial role during the immune response. The channel forms oligomeric complexes by associating with several modulatory subunits. KCNE4, one of the five members of the KCNE family, binds to Kv1.3, altering channel activity and membrane expression. The...

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Detalles Bibliográficos
Autores principales: Solé, Laura, Sastre, Daniel, Colomer-Molera, Magalí, Vallejo-Gracia, Albert, Roig, Sara R., Pérez-Verdaguer, Mireia, Lillo, Pilar, Tamkun, Michael M., Felipe, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290415/
https://www.ncbi.nlm.nih.gov/pubmed/32370164
http://dx.doi.org/10.3390/cells9051128