P38 MAPK Promotes Migration and Metastatic Activity of BRAF Mutant Melanoma Cells by Inducing Degradation of PMCA4b

Metastatic melanoma is the most aggressive type of skin cancer. Previously, we identified the plasma membrane Ca(2+) pump isoform 4b (PMCA4b or ATP2B4) as a putative metastasis suppressor in BRAF mutant melanoma cells. Metastasis suppressors are often downregulated in cancer, therefore, it is import...

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Detalles Bibliográficos
Autores principales: Naffa, Randa, Vogel, Lisa, Hegedűs, Luca, Pászty, Katalin, Tóth, Sarolta, Kelemen, Kornélia, Singh, Neha, Reményi, Attila, Kállay, Enikő, Cserepes, Mihály, Tóvári, József, Grusch, Michael, Enyedi, Ágnes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290426/
https://www.ncbi.nlm.nih.gov/pubmed/32414111
http://dx.doi.org/10.3390/cells9051209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290426/
https://www.ncbi.nlm.nih.gov/pubmed/32414111
http://dx.doi.org/10.3390/cells9051209

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