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L-Selectin/CD62L Is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men

CD62L (L-Selectin) dependent lymphocyte infiltration is known to induce inflammatory bowel disease (IBD), while its function in the liver, especially in non-alcoholic steatohepatitis (NASH), remains unclear. We here investigated the functional role of CD62L in NASH in humans as well as in two mouse...

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Detalles Bibliográficos
Autores principales: Drescher, Hannah K., Schippers, Angela, Rosenhain, Stefanie, Gremse, Felix, Bongiovanni, Laura, de Bruin, Alain, Eswaran, Sreepradha, Gallage, Suchira U., Pfister, Dominik, Szydlowska, Marta, Heikenwalder, Mathias, Weiskirchen, Sabine, Wagner, Norbert, Trautwein, Christian, Weiskirchen, Ralf, Kroy, Daniela C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290433/
https://www.ncbi.nlm.nih.gov/pubmed/32365632
http://dx.doi.org/10.3390/cells9051106