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Lung Tumor Cell-Derived Exosomes Promote M2 Macrophage Polarization

Cellular cross-talk within the tumor microenvironment (TME) by exosomes is known to promote tumor progression. Tumor promoting macrophages with an M2 phenotype are suppressors of anti-tumor immunity. However, the impact of tumor-derived exosomes in modulating macrophage polarization in the lung TME...

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Detalles Bibliográficos
Autores principales: Pritchard, Alexandra, Tousif, Sultan, Wang, Yong, Hough, Kenneth, Khan, Saad, Strenkowski, John, Chacko, Balu K., Darley-Usmar, Victor M., Deshane, Jessy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290460/
https://www.ncbi.nlm.nih.gov/pubmed/32456301
http://dx.doi.org/10.3390/cells9051303