Tubulin Resists Degradation by Cereblon-Recruiting PROTACs

Dysregulation of microtubules and tubulin homeostasis has been linked to developmental disorders, neurodegenerative diseases, and cancer. In general, both microtubule-stabilizing and destabilizing agents have been powerful tools for studies of microtubule cytoskeleton and as clinical agents in oncol...

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Detalles Bibliográficos
Autores principales: Gasic, Ivana, Groendyke, Brian J., Nowak, Radosław P., Yuan, J. Christine, Kalabathula, Joann, Fischer, Eric S., Gray, Nathanael S., Mitchison, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290497/
https://www.ncbi.nlm.nih.gov/pubmed/32349222
http://dx.doi.org/10.3390/cells9051083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290497/
https://www.ncbi.nlm.nih.gov/pubmed/32349222
http://dx.doi.org/10.3390/cells9051083

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