Recombinant Myxoma Virus Expressing Walleye Dermal Sarcoma Virus orfC Is Attenuated in Rabbits

The poxvirus, myxoma virus (MYXV) has shown efficacy as an oncolytic virus (OV) in some cancer models. However, MYXV replication within murine cancer models and spontaneous canine sarcomas is short-lived. In mice, successful treatment of tumors requires frequent injections with MYXV. We hypothesize...

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Detalles Bibliográficos
Autores principales: Ashton, Laura V., Quackenbush, Sandra L., Castle, Jake, Wilson, Garin, McCoy, Jasmine, Jordan, Mariah, MacNeill, Amy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290507/
https://www.ncbi.nlm.nih.gov/pubmed/32397134
http://dx.doi.org/10.3390/v12050517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290507/
https://www.ncbi.nlm.nih.gov/pubmed/32397134
http://dx.doi.org/10.3390/v12050517

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