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The anti-tumor effect of taxifolin on lung cancer via suppressing stemness and epithelial-mesenchymal transition in vitro and oncogenesis in nude mice

BACKGROUND: Taxifolin is a natural flavonoid with anti-oxidant and anti-proliferative properties. In this study, we investigated the stemness-related inhibitory effects of taxifolin in two lung cancer cell lines, A549 and H1975, as well as in A549 xenografts. METHODS: A549 and H1975 cells, as well a...

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Detalles Bibliográficos
Autores principales: Wang, Ronghua, Zhu, Xianjun, Wang, Qing, Li, Xiaoqing, Wang, Enling, Zhao, Qianqian, Wang, Qianqian, Cao, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290558/
https://www.ncbi.nlm.nih.gov/pubmed/32566617
http://dx.doi.org/10.21037/atm-20-3329