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Investigating Human Mitochondrial Genomes in Single Cells

Mitochondria host multiple copies of their own small circular genome that has been extensively studied to trace the evolution of the modern eukaryotic cell and discover important mutations linked to inherited diseases. Whole genome and exome sequencing have enabled the study of mtDNA in a large numb...

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Detalles Bibliográficos
Autores principales: Diroma, Maria Angela, Varvara, Angelo Sante, Attimonelli, Marcella, Pesole, Graziano, Picardi, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290567/
https://www.ncbi.nlm.nih.gov/pubmed/32403285
http://dx.doi.org/10.3390/genes11050534