Activation of Steroidogenesis, Anti-Apoptotic Activity, and Proliferation in Porcine Granulosa Cells by RUNX1 Is Negatively Regulated by H3K27me3 Transcriptional Repression

H3K27me3 is an epigenetic modification that results in the repression of gene transcription. The transcription factor RUNX1 (the runt-related transcription factor 1) influences granulosa cells’ growth and ovulation. This research uses ELISA, flow cytometry, EDU, ChIP-PCR, WB and qPCR to investigate...

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Detalles Bibliográficos
Autores principales: Zhong, Yuyi, Li, Liying, He, Yingting, He, Bo, Li, Zhonghui, Zhang, Zhe, Zhang, Hao, Yuan, Xiaolong, Li, Jiaqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290568/
https://www.ncbi.nlm.nih.gov/pubmed/32365901
http://dx.doi.org/10.3390/genes11050495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290568/
https://www.ncbi.nlm.nih.gov/pubmed/32365901
http://dx.doi.org/10.3390/genes11050495

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