Cargando…

Activation of Steroidogenesis, Anti-Apoptotic Activity, and Proliferation in Porcine Granulosa Cells by RUNX1 Is Negatively Regulated by H3K27me3 Transcriptional Repression

H3K27me3 is an epigenetic modification that results in the repression of gene transcription. The transcription factor RUNX1 (the runt-related transcription factor 1) influences granulosa cells’ growth and ovulation. This research uses ELISA, flow cytometry, EDU, ChIP-PCR, WB and qPCR to investigate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhong, Yuyi, Li, Liying, He, Yingting, He, Bo, Li, Zhonghui, Zhang, Zhe, Zhang, Hao, Yuan, Xiaolong, Li, Jiaqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290568/ https://www.ncbi.nlm.nih.gov/pubmed/32365901 http://dx.doi.org/10.3390/genes11050495

Ejemplares similares

MIR143 Inhibits Steroidogenesis and Induces Apoptosis Repressed by H3K27me3 in Granulosa Cells
por: Zhong, Yuyi, et al.
Publicado: (2020)

P65 Targets FGFR1 to Regulate the Survival of Ovarian Granulosa Cells
por: Yuan, Xiaolong, et al.
Publicado: (2019)

C/EBPβ Promotes STAT3 Expression and Affects Cell Apoptosis and Proliferation in Porcine Ovarian Granulosa Cells
por: Yuan, Xiaolong, et al.
Publicado: (2018)

MiR-126-3p inhibits apoptosis and promotes proliferation by targeting phosphatidylinositol 3-kinase regulatory subunit 2 in porcine ovarian granulosa cells
por: Zhou, Xiaofeng, et al.
Publicado: (2020)

KISS1 Suppresses Apoptosis and Stimulates the Synthesis of E2 in Porcine Ovarian Granulosa Cells
por: Xin, Xiaoping, et al.
Publicado: (2019)

Mechanism of SCD Participation in Lipid Droplet-Mediated Steroidogenesis in Goose Granulosa Cells
por: Yuan, Xin, et al.
Publicado: (2022)

Bisphenol S Impaired Human Granulosa Cell Steroidogenesis in Vitro
por: Amar, Sarah, et al.
Publicado: (2020)

FASN-Mediated Lipid Metabolism Regulates Goose Granulosa Cells Apoptosis and Steroidogenesis
por: Chen, Xi, et al.
Publicado: (2020)

HIF1 driven transcriptional activity regulates steroidogenesis and proliferation of bovine granulosa cells
por: Baddela, Vijay Simha, et al.
Publicado: (2020)

miR-202-5p Inhibits Lipid Metabolism and Steroidogenesis of Goose Hierarchical Granulosa Cells by Targeting ACSL3
por: Ran, Mingxia, et al.
Publicado: (2023)

The Phytoestrogen Quercetin Impairs Steroidogenesis and Angiogenesis in Swine Granulosa Cells In Vitro
por: Santini, Sujen Eleonora, et al.
Publicado: (2009)

Docosahexaenoic acid (DHA) effects on proliferation and steroidogenesis of bovine granulosa cells
por: Maillard, Virginie, et al.
Publicado: (2018)

Mitochondrial Function in Modulating Human Granulosa Cell Steroidogenesis and Female Fertility
por: Sreerangaraja Urs, Dilip Bhargava, et al.
Publicado: (2020)

In Vitro Effects of Enniatin A on Steroidogenesis and Proliferation of Bovine Granulosa Cells
por: Chiminelli, Ilaria, et al.
Publicado: (2022)

Apelin and Apelin Receptor in Follicular Granulosa Cells of Buffalo Ovaries: Expression and Regulation of Steroidogenesis
por: Shokrollahi, Borhan, et al.
Publicado: (2022)

Synergistic inhibition of csal1 and csal3 in granulosa cell proliferation and steroidogenesis of hen ovarian prehierarchical development(†)
por: Zhu, Hongyan, et al.
Publicado: (2019)

Effect of adiponectin on bovine granulosa cell steroidogenesis, oocyte maturation and embryo development
por: Maillard, Virginie, et al.
Publicado: (2010)

Follicular stage-dependent regulation of apoptosis and steroidogenesis by prohibitin in rat granulosa cells
por: Wang, Qi, et al.
Publicado: (2013)

Involvement of BMP-15 in Glucocorticoid Actions on Ovarian Steroidogenesis by Rat Granulosa Cells
por: Kashino, Chiaki, et al.
Publicado: (2021)

Mitoguardin2 Is Associated With Hyperandrogenism and Regulates Steroidogenesis in Human Ovarian Granulosa Cells
por: Yan, Ming-Qi, et al.
Publicado: (2023)

Paracrine Regulation of Steroidogenesis in Theca Cells by Granulosa Cells Derived from Mouse Preantral Follicles
por: Liu, Xiaoqiang, et al.
Publicado: (2015)

Transcriptome Analysis of Porcine Granulosa Cells in Healthy and Atretic Follicles: Role of Steroidogenesis and Oxidative Stress
por: Meng, Li, et al.
Publicado: (2020)

Leptin interferes with 3',5'-Cyclic Adenosine Monophosphate (cAMP) signaling to inhibit steroidogenesis in human granulosa cells
por: Lin, Qing, et al.
Publicado: (2009)

LncGSAR Controls Ovarian Granulosa Cell Steroidogenesis via Sponging MiR-125b to Activate SCAP/SREBP Pathway
por: Wang, Yong, et al.
Publicado: (2022)

Direct rosiglitazone action on steroidogenesis and proinflammatory factor production in human granulosa-lutein cells
por: Chen, Qiuju, et al.
Publicado: (2009)

RNAi-mediated knockdown of INHBB increases apoptosis and inhibits steroidogenesis in mouse granulosa cells
por: M’BAYE, Mohamed, et al.
Publicado: (2015)

MON-012 The Direct Effect of Kisspeptin on Human Ovarian Granulosa Cells to Regulate Steroidogenesis
por: Qin, Lixian, et al.
Publicado: (2020)

Increased Formation of Follicular Antrum in Aquaporin-8-Deficient Mice Is Due to Defective Proliferation and Migration, and Not Steroidogenesis of Granulosa Cells
por: Wang, Dejiang, et al.
Publicado: (2018)

Brain-derived neurotrophic factor promotes human granulosa-like tumor cell steroidogenesis and proliferation by activating the FSH receptor-mediated signaling pathway
por: Xie, Min, et al.
Publicado: (2017)

Oleic acid reduces steroidogenesis by changing the lipid type stored in lipid droplets of ovarian granulosa cells
por: Zhou, Xiaoge, et al.
Publicado: (2022)

SUN-193 Effects of Aldosterone on Ovarian Steroidogenesis and Involvement of BMP Action in Rat Granulosa Cells
por: Nakano, Yasuhiro, et al.
Publicado: (2019)

Spexin role in human granulosa cells physiology and PCOS: expression and negative impact on steroidogenesis and proliferation
por: Kurowska, Patrycja, et al.
Publicado: (2023)

RNA-seq based gene expression analysis of ovarian granulosa cells exposed to zearalenone in vitro: significance to steroidogenesis
por: Zhang, Guo-Liang, et al.
Publicado: (2017)

BMI1 Drives Steroidogenesis Through Epigenetically Repressing the p38 MAPK Pathway
por: Yu, Jun, et al.
Publicado: (2021)

Neuromedin S Regulates Steroidogenesis through Maintaining Mitochondrial Morphology and Function via NMUR2 in Goat Ovarian Granulosa Cells
por: Sun, Xuan, et al.
Publicado: (2022)

The EZH2-H3K27me3 axis modulates aberrant transcription and apoptosis in cyclophosphamide-induced ovarian granulosa cell injury
por: Chen, Yingyan, et al.
Publicado: (2023)

The Anti-Epileptic Drug Valproic Acid (VPA) Inhibits Steroidogenesis in Bovine Theca and Granulosa Cells In Vitro
por: Glister, Claire, et al.
Publicado: (2012)

MON-227 Roles of Clock Expression Modulated by BMP-7 in Ovarian Steroidogenesis by Human Granulosa Cells
por: Nagao, Satoko, et al.
Publicado: (2019)

ODP407 Effects of Leptin and Ghrelin on Ovarian Steroidogenesis and Involvement of BMP Action in Rat Granulosa Cells.
por: Nakano, Yasuhiro, et al.
Publicado: (2022)

Bisphenol A and bisphenol S both disrupt ovine granulosa cell steroidogenesis but through different molecular pathways
por: Téteau, Ophélie, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8gh17fubf7o0un1e81838akr3t