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Activation of Steroidogenesis, Anti-Apoptotic Activity, and Proliferation in Porcine Granulosa Cells by RUNX1 Is Negatively Regulated by H3K27me3 Transcriptional Repression
H3K27me3 is an epigenetic modification that results in the repression of gene transcription. The transcription factor RUNX1 (the runt-related transcription factor 1) influences granulosa cells’ growth and ovulation. This research uses ELISA, flow cytometry, EDU, ChIP-PCR, WB and qPCR to investigate...
Autores principales: | Zhong, Yuyi, Li, Liying, He, Yingting, He, Bo, Li, Zhonghui, Zhang, Zhe, Zhang, Hao, Yuan, Xiaolong, Li, Jiaqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290568/ https://www.ncbi.nlm.nih.gov/pubmed/32365901 http://dx.doi.org/10.3390/genes11050495 |
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