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The Robust Restriction of Zika Virus by Type-I Interferon in A549 Cells Varies by Viral Lineage and Is Not Determined by IFITM3

Type-I interferon (IFN-I) is a major antiviral host response but its impact on Zika virus (ZIKV) replication is not well defined, particularly as it relates to different circulating strains. Interferon stimulated genes (ISGs) that inhibit ZIKV, such as IFITM3, have been identified largely using over...

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Detalles Bibliográficos
Autores principales: Gobillot, Theodore A., Humes, Daryl, Sharma, Amit, Kikawa, Caroline, Overbaugh, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290589/
https://www.ncbi.nlm.nih.gov/pubmed/32370187
http://dx.doi.org/10.3390/v12050503