Cargando…
Concerted EP2 and EP4 Receptor Signaling Stimulates Autocrine Prostaglandin E(2) Activation in Human Podocytes
Glomerular hyperfiltration is an important mechanism in the development of albuminuria. During hyperfiltration, podocytes are exposed to increased fluid flow shear stress (FFSS) in Bowman’s space. Elevated Prostaglandin E2 (PGE(2)) synthesis and upregulated cyclooxygenase 2 (Cox2) are associated wit...
Autores principales: | Mangelsen, Eva, Rothe, Michael, Schulz, Angela, Kourpa, Aikaterini, Panáková, Daniela, Kreutz, Reinhold, Bolbrinker, Juliane |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290667/ https://www.ncbi.nlm.nih.gov/pubmed/32438662 http://dx.doi.org/10.3390/cells9051256 |
Ejemplares similares
-
Role of prostaglandin E receptor subtypes EP2 and EP4 in autocrine and paracrine functions of vascular endothelial growth factor in the inner ear
por: Hori, Ryusuke, et al.
Publicado: (2010) -
Role of EP(2) and EP(4) receptors in airway microvascular leak induced by prostaglandin E(2)
por: Jones, Victoria C, et al.
Publicado: (2016) -
Cloning and expression of the rabbit prostaglandin EP2 receptor
por: Guan, Youfei, et al.
Publicado: (2002) -
Prostaglandin E2 promotes human CD34(+) cells homing through EP2 and EP4 in vitro
por: Wang, Yaqun, et al.
Publicado: (2017) -
Characterization of the Signaling Modalities of Prostaglandin E2 Receptors EP2 and EP4 Reveals Crosstalk and a Role for Microtubules
por: Vleeshouwers, Ward, et al.
Publicado: (2021)