Targeting the IGF-Axis for Cancer Therapy: Development and Validation of an IGF-Trap as a Potential Drug

The insulin-like growth factor (IGF)-axis was implicated in cancer progression and identified as a clinically important therapeutic target. Several IGF-I receptor (IGF-IR) targeting drugs including humanized monoclonal antibodies have advanced to phase II/III clinical trials, but to date, have not p...

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Detalles Bibliográficos
Autores principales: Chen, Yinhsuan Michely, Qi, Shu, Perrino, Stephanie, Hashimoto, Masakazu, Brodt, Pnina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290707/
https://www.ncbi.nlm.nih.gov/pubmed/32365498
http://dx.doi.org/10.3390/cells9051098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290707/
https://www.ncbi.nlm.nih.gov/pubmed/32365498
http://dx.doi.org/10.3390/cells9051098

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