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A New Pathway Promotes Adaptation of Human Glioblastoma Cells to Glucose Starvation

Adaptation of glioblastoma to caloric restriction induces compensatory changes in tumor metabolism that are incompletely known. Here we show that in human glioblastoma cells maintained in exhausted medium, SHC adaptor protein 3 (SHC3) increases due to down-regulation of SHC3 protein degradation. Thi...

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Detalles Bibliográficos
Autores principales: Azzalin, Alberto, Brambilla, Francesca, Arbustini, Eloisa, Basello, Katia, Speciani, Attilio, Mauri, Pierluigi, Bezzi, Paola, Magrassi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290719/
https://www.ncbi.nlm.nih.gov/pubmed/32443613
http://dx.doi.org/10.3390/cells9051249