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TFEB Modulates p21/WAF1/CIP1 during the DNA Damage Response

The MiT/TFE family of transcription factors (MITF, TFE3, and TFEB), which control transcriptional programs for autophagy and lysosome biogenesis have emerged as regulators of energy metabolism in cancer. Thus, their activation increases lysosomal catabolic function to sustain cancer cell growth and...

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Detalles Bibliográficos
Autores principales: Pisonero-Vaquero, Sandra, Soldati, Chiara, Cesana, Marcella, Ballabio, Andrea, Medina, Diego Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290768/
https://www.ncbi.nlm.nih.gov/pubmed/32397616
http://dx.doi.org/10.3390/cells9051186