Cardiomyocyte-Specific Deletion of Orai1 Reveals Its Protective Role in Angiotensin-II-Induced Pathological Cardiac Remodeling

Pathological cardiac remodeling correlates with chronic neurohumoral stimulation and abnormal Ca(2+) signaling in cardiomyocytes. Store-operated calcium entry (SOCE) has been described in adult and neonatal murine cardiomyocytes, and Orai1 proteins act as crucial ion-conducting constituents of this...

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Detalles Bibliográficos
Autores principales: Segin, Sebastian, Berlin, Michael, Richter, Christin, Medert, Rebekka, Flockerzi, Veit, Worley, Paul, Freichel, Marc, Camacho Londoño, Juan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290784/
https://www.ncbi.nlm.nih.gov/pubmed/32354146
http://dx.doi.org/10.3390/cells9051092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290784/
https://www.ncbi.nlm.nih.gov/pubmed/32354146
http://dx.doi.org/10.3390/cells9051092

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