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Fibrillarin Ribonuclease Activity is Dependent on the GAR Domain and Modulated by Phospholipids
Fibrillarin is a highly conserved nucleolar methyltransferase responsible for ribosomal RNA methylation across evolution from Archaea to humans. It has been reported that fibrillarin is involved in the methylation of histone H2A in nucleoli and other processes, including viral progression, cellular...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290794/ https://www.ncbi.nlm.nih.gov/pubmed/32384686 http://dx.doi.org/10.3390/cells9051143 |