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Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation

Clinical studies have established a connection between oxidative stress, aging, and atherogenesis. These factors contribute to senescence and inflammation in the endothelium and significant reductions in endothelium-dependent vasoreactivity in aged patients. Tissue-engineered blood vessels (TEBVs) r...

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Detalles Bibliográficos
Autores principales: Salmon, Ellen E., Breithaupt, Jason J., Truskey, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290800/
https://www.ncbi.nlm.nih.gov/pubmed/32455928
http://dx.doi.org/10.3390/cells9051292