ONX 0914 Lacks Selectivity for the Cardiac Immunoproteasome in CoxsackievirusB3 Myocarditis of NMRI Mice and Promotes Virus-Mediated Tissue Damage

Inhibition of proteasome function by small molecules is highly efficacious in cancer treatment. Other than non-selective proteasome inhibitors, immunoproteasome-specific inhibitors allow for specific targeting of the proteasome in immune cells and the profound anti-inflammatory potential of such com...

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Detalles Bibliográficos
Autores principales: Neumaier, Hannah Louise, Harel, Shelly, Klingel, Karin, Kaya, Ziya, Heuser, Arnd, Kespohl, Meike, Beling, Antje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290815/
https://www.ncbi.nlm.nih.gov/pubmed/32354159
http://dx.doi.org/10.3390/cells9051093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290815/
https://www.ncbi.nlm.nih.gov/pubmed/32354159
http://dx.doi.org/10.3390/cells9051093

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