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Allosteric Antagonism of the A(2A) Adenosine Receptor by a Series of Bitopic Ligands
Allosteric antagonism by bitopic ligands, as reported for many receptors, is a distinct modulatory mechanism. Although several bitopic A(2A) adenosine receptor (A(2A)AR) ligand classes were reported as pharmacological tools, their receptor binding and functional antagonism patterns, i.e., allosteric...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290864/ https://www.ncbi.nlm.nih.gov/pubmed/32408534 http://dx.doi.org/10.3390/cells9051200 |