In Vitro-Generated Hypertrophic-Like Adipocytes Displaying PPARG Isoforms Unbalance Recapitulate Adipocyte Dysfunctions In Vivo

Reduced neo-adipogenesis and dysfunctional lipid-overloaded adipocytes are hallmarks of hypertrophic obesity linked to insulin resistance. Identifying molecular features of hypertrophic adipocytes requires appropriate in vitro models. We describe the generation of a model of human hypertrophic-like...

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Detalles Bibliográficos
Autores principales: Aprile, Marianna, Cataldi, Simona, Perfetto, Caterina, Ambrosio, Maria Rosaria, Italiani, Paola, Tatè, Rosarita, Blüher, Matthias, Ciccodicola, Alfredo, Costa, Valerio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290899/
https://www.ncbi.nlm.nih.gov/pubmed/32455814
http://dx.doi.org/10.3390/cells9051284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290899/
https://www.ncbi.nlm.nih.gov/pubmed/32455814
http://dx.doi.org/10.3390/cells9051284

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