Lactulose and Melibiose Inhibit α-Synuclein Aggregation and Up-Regulate Autophagy to Reduce Neuronal Vulnerability

Parkinson’s disease (PD) is a neurodegenerative disease characterized by selective dopaminergic (DAergic) neuronal degeneration in the substantia nigra (SN) and proteinaceous α-synuclein-positive Lewy bodies and Lewy neuritis. As a chemical chaperone to promote protein stability and an autophagy ind...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Chiung Mei, Lin, Chih-Hsin, Wu, Yih-Ru, Yen, Chien-Yu, Huang, Yu-Ting, Lin, Jia-Lan, Lin, Chung-Yin, Chen, Wan-Ling, Chao, Chih-Ying, Lee-Chen, Guey-Jen, Su, Ming-Tsan, Chang, Kuo-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290909/
https://www.ncbi.nlm.nih.gov/pubmed/32429337
http://dx.doi.org/10.3390/cells9051230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290909/
https://www.ncbi.nlm.nih.gov/pubmed/32429337
http://dx.doi.org/10.3390/cells9051230

Ejemplares similares