Cytotoxic 4-Hydroxyprorocentrolide and Prorocentrolide C from Cultured Dinoflagellate Prorocentrum lima Induce Human Cancer Cell Death through Apoptosis and Cell Cycle Arrest

Prorocentrolide and its analogs, the novel naturally derived antitumor agents, have recently been identified in the dinoflagellate Prorocentrum lima. In the current study, the underlying inhibitory mechanisms of 4-hydroxyprorocentrolide (1) and prorocentrolide C (2) on the proliferation of human car...

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Detalles Bibliográficos
Autores principales: Lee, Seon Min, Kim, Na-Hyun, Jeong, Eun Ju, Rho, Jung-Rae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290926/
https://www.ncbi.nlm.nih.gov/pubmed/32392799
http://dx.doi.org/10.3390/toxins12050304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290926/
https://www.ncbi.nlm.nih.gov/pubmed/32392799
http://dx.doi.org/10.3390/toxins12050304

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