Novel Multiplex Droplet Digital PCR Assays to Monitor Minimal Residual Disease in Chronic Myeloid Leukemia Patients Showing Atypical BCR-ABL1 Transcripts

BCR-ABL1 fusion transcript is the minimal residual disease marker in chronic myeloid leukemia; 2% of patients show unusual breakpoints generating atypical transcripts, not quantifiable by standardized real-time PCR (RT–PCR). Response monitoring is performed by non-quantitative NESTED PCR, useless fo...

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Detalles Bibliográficos
Autores principales: Petiti, Jessica, Lo Iacono, Marco, Dragani, Matteo, Pironi, Lucrezia, Fantino, Cristina, Rapanotti, Maria Cristina, Quarantelli, Fabrizio, Izzo, Barbara, Divona, Mariadomenica, Rege-Cambrin, Giovanna, Saglio, Giuseppe, Gottardi, Enrico Marco, Cilloni, Daniela, Fava, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290999/
https://www.ncbi.nlm.nih.gov/pubmed/32414125
http://dx.doi.org/10.3390/jcm9051457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290999/
https://www.ncbi.nlm.nih.gov/pubmed/32414125
http://dx.doi.org/10.3390/jcm9051457

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