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Unmasking Intra-Tumoral Heterogeneity and Clonal Evolution in NF1-MPNST

Sarcomas are highly aggressive cancers that have a high propensity for metastasis, fail to respond to conventional therapies, and carry a poor 5-year survival rate. This is particularly true for patients with neurofibromatosis type 1 (NF1), in which 8%–13% of affected individuals will develop a mali...

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Detalles Bibliográficos
Autores principales: Moon, Chang-In, Tompkins, William, Wang, Yuxi, Godec, Abigail, Zhang, Xiaochun, Pipkorn, Patrik, Miller, Christopher A., Dehner, Carina, Dahiya, Sonika, Hirbe, Angela C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291009/
https://www.ncbi.nlm.nih.gov/pubmed/32369930
http://dx.doi.org/10.3390/genes11050499