Effects of Circulating HMGB-1 and Histones on Cardiomyocytes–Hemadsorption of These DAMPs as Therapeutic Strategy after Multiple Trauma

Background and purpose: The aim of the study was to determine the effects of post-traumatically released High Mobility Group Box-1 protein (HMGB1) and extracellular histones on cardiomyocytes (CM). We also evaluated a therapeutic option to capture circulating histones after trauma, using a hemadsorp...

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Detalles Bibliográficos
Autores principales: Weber, Birte, Lackner, Ina, Baur, Meike, Fois, Giorgio, Gebhard, Florian, Marzi, Ingo, Schrezenmeier, Hubert, Relja, Borna, Kalbitz, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291040/
https://www.ncbi.nlm.nih.gov/pubmed/32403440
http://dx.doi.org/10.3390/jcm9051421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291040/
https://www.ncbi.nlm.nih.gov/pubmed/32403440
http://dx.doi.org/10.3390/jcm9051421

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