Mouse Gonad Development in the Absence of the Pro-Ovary Factor WNT4 and the Pro-Testis Factor SOX9

The transcription factors SRY and SOX9 and RSPO1/WNT4/β-Catenin signaling act as antagonistic pathways to drive testis and ovary development respectively, from a common gonadal primordium in mouse embryos. In this work, we took advantage of a double knockout mouse model to study gonadal development...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Furong, Richardson, Nainoa, Albina, Audrey, Chaboissier, Marie-Christine, Perea-Gomez, Aitana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291083/
https://www.ncbi.nlm.nih.gov/pubmed/32365547
http://dx.doi.org/10.3390/cells9051103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291083/
https://www.ncbi.nlm.nih.gov/pubmed/32365547
http://dx.doi.org/10.3390/cells9051103

Ejemplares similares