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Mouse Gonad Development in the Absence of the Pro-Ovary Factor WNT4 and the Pro-Testis Factor SOX9

The transcription factors SRY and SOX9 and RSPO1/WNT4/β-Catenin signaling act as antagonistic pathways to drive testis and ovary development respectively, from a common gonadal primordium in mouse embryos. In this work, we took advantage of a double knockout mouse model to study gonadal development...

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Detalles Bibliográficos
Autores principales:	Tang, Furong, Richardson, Nainoa, Albina, Audrey, Chaboissier, Marie-Christine, Perea-Gomez, Aitana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291083/ https://www.ncbi.nlm.nih.gov/pubmed/32365547 http://dx.doi.org/10.3390/cells9051103

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