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Deletion of Cardiomyocyte Glycogen Synthase Kinase-3 Beta (GSK-3β) Improves Systemic Glucose Tolerance with Maintained Heart Function in Established Obesity

Obesity is an independent risk factor for cardiovascular diseases (CVD), including heart failure. Thus, there is an urgent need to understand the molecular mechanism of obesity-associated cardiac dysfunction. We recently reported the critical role of cardiomyocyte (CM) Glycogen Synthase Kinase-3 bet...

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Detalles Bibliográficos
Autores principales: Gupte, Manisha, Umbarkar, Prachi, Singh, Anand Prakash, Zhang, Qinkun, Tousif, Sultan, Lal, Hind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291092/
https://www.ncbi.nlm.nih.gov/pubmed/32365965
http://dx.doi.org/10.3390/cells9051120