Cargando…
Deletion of Cardiomyocyte Glycogen Synthase Kinase-3 Beta (GSK-3β) Improves Systemic Glucose Tolerance with Maintained Heart Function in Established Obesity
Obesity is an independent risk factor for cardiovascular diseases (CVD), including heart failure. Thus, there is an urgent need to understand the molecular mechanism of obesity-associated cardiac dysfunction. We recently reported the critical role of cardiomyocyte (CM) Glycogen Synthase Kinase-3 bet...
Autores principales: | Gupte, Manisha, Umbarkar, Prachi, Singh, Anand Prakash, Zhang, Qinkun, Tousif, Sultan, Lal, Hind |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291092/ https://www.ncbi.nlm.nih.gov/pubmed/32365965 http://dx.doi.org/10.3390/cells9051120 |
Ejemplares similares
-
Isoform-Specific Role of GSK-3 in High Fat Diet Induced Obesity and Glucose Intolerance
por: Gupte, Manisha, et al.
Publicado: (2022) -
Cardiomyocyte SMAD4-Dependent TGF-β Signaling is Essential to Maintain Adult Heart Homeostasis
por: Umbarkar, Prachi, et al.
Publicado: (2019) -
A Pharmacovigilance Study of Hydroxychloroquine Cardiac Safety Profile: Potential Implication in COVID-19 Mitigation
por: Singh, Anand Prakash, et al.
Publicado: (2020) -
Mechanisms of Fibroblast Activation and Myocardial Fibrosis: Lessons Learned from FB-Specific Conditional Mouse Models
por: Umbarkar, Prachi, et al.
Publicado: (2021) -
Glycogen Synthase Kinase-3 (GSK-3)-Targeted Therapy and Imaging
por: Pandey, Mukesh K., et al.
Publicado: (2016)