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Fractionation-Dependent Radiosensitization by Molecular Targeting of Nek1

NIMA (never-in-mitosis gene A)-related kinase 1 (Nek1) is shown to impact on different cellular pathways such as DNA repair, checkpoint activation, and apoptosis. Its role as a molecular target for radiation sensitization of malignant cells, however, remains elusive. Stably transduced doxycycline (D...

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Detalles Bibliográficos
Autores principales: Freund, Isabel, Hehlgans, Stephanie, Martin, Daniel, Ensminger, Michael, Fokas, Emmanouil, Rödel, Claus, Löbrich, Markus, Rödel, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291120/
https://www.ncbi.nlm.nih.gov/pubmed/32429458
http://dx.doi.org/10.3390/cells9051235