Cargando…
Fractionation-Dependent Radiosensitization by Molecular Targeting of Nek1
NIMA (never-in-mitosis gene A)-related kinase 1 (Nek1) is shown to impact on different cellular pathways such as DNA repair, checkpoint activation, and apoptosis. Its role as a molecular target for radiation sensitization of malignant cells, however, remains elusive. Stably transduced doxycycline (D...
Autores principales: | Freund, Isabel, Hehlgans, Stephanie, Martin, Daniel, Ensminger, Michael, Fokas, Emmanouil, Rödel, Claus, Löbrich, Markus, Rödel, Franz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291120/ https://www.ncbi.nlm.nih.gov/pubmed/32429458 http://dx.doi.org/10.3390/cells9051235 |
Ejemplares similares
-
Tumor Suppressor Protein p53 and Inhibitor of Apoptosis Proteins in Colorectal Cancer—A Promising Signaling Network for Therapeutic Interventions
por: Güllülü, Ömer, et al.
Publicado: (2021) -
Prognostic Impact of Caspase-8, CDK9 and Phospho-CDK9 (Thr 186) Expression in Patients with Uterine Cervical Cancer Treated with Definitive Chemoradiation and Brachytherapy
por: Fleischmann, Maximilian, et al.
Publicado: (2022) -
Peripheral Leukocytosis Is Inversely Correlated with Intratumoral CD8+ T-Cell Infiltration and Associated with Worse Outcome after Chemoradiotherapy in Anal Cancer
por: Martin, Daniel, et al.
Publicado: (2017) -
C-Reactive Protein-to-Albumin Ratio as Prognostic Marker for Anal Squamous Cell Carcinoma Treated With Chemoradiotherapy
por: Martin, Daniel, et al.
Publicado: (2019) -
Eine Monotherapie mit Immuncheckpointblockade führt bei Patienten mit Rektumkarzinom und Mikrosatelliteninstabilität zur klinischen Komplettremission
por: Diefenhardt, Markus, et al.
Publicado: (2022)